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Laparoscopic surgery for pancreatic lesions: current status and future

Taiping Zhang, Xiao Du, Yupei Zhao

Frontiers of Medicine 2011, Volume 5, Issue 3,   Pages 277-282 doi: 10.1007/s11684-011-0147-5

Abstract: Laparoscopic pancreatic surgery has been gaining increasing recognition in recent years, and its practiceProspective, randomized, controlled trials of laparoscopic operation versus open pancreatic surgery arenecessary to justify the wide application and routine practice of the laparoscopic procedure for pancreatic

Keywords： minimally invasive surgery     pancreatic surgery     pancreatic neoplasm     distal pancreatic lesions     pancreatic    

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Robotic distal pancreatectomy versus conventional laparoscopic distal pancreatectomy: a comparative study for short-term outcomes

Eric C. H. Lai,Chung Ngai Tang

Frontiers of Medicine 2015, Volume 9, Issue 3,   Pages 356-360 doi: 10.1007/s11684-015-0404-0

Abstract:

Robotic system has been increasingly used in pancreatectomy. However, the effectiveness of this method remains uncertain. This study compared the surgical outcomes between robot-assisted laparoscopic distal pancreatectomy and conventional laparoscopic distal pancreatectomy. During a 15-year period, 35 patients underwent minimally invasive approach of distal pancreatectomy in our center. Seventeen of these patients had robot-assisted laparoscopic approach, and the remaining 18 had conventional laparoscopic approach. Their operative parameters and perioperative outcomes were analyzed retrospectively in a prospective database. The mean operating time in the robotic group (221.4 min) was significantly longer than that in the laparoscopic group (173.6 min) (P = 0.026). Both robotic and conventional laparoscopic groups presented no significant difference in spleen-preservation rate (52.9% vs. 38.9%) (P = 0.505), operative blood loss (100.3 ml vs. 268.3 ml) (P = 0.29), overall morbidity rate (47.1% vs. 38.9%) (P = 0.73), and post-operative hospital stay (11.4 days vs. 14.2 days) (P = 0.46). Both groups also showed no perioperative mortality. Similar outcomes were observed in robotic distal pancreatectomy and conventional laparoscopic approach. However, robotic approach tended to have the advantages of less blood loss and shorter hospital stay. Further studies are necessary to determine the clinical position of robotic distal pancreatectomy.

Keywords： distal pancreatectomy     pancreatic neoplasm     robotic surgery    

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Prevention and treatment of pancreatic fistula after pancreatic body and tail resection: current status

Li Jiang, Deng Ning, Xiaoping Chen

Frontiers of Medicine 2020, Volume 14, Issue 3,   Pages 251-261 doi: 10.1007/s11684-019-0727-3

Abstract: Postoperative pancreatic fistula (POPF) is the most common and critical complication after pancreaticHow to effectively reduce the occurrence of pancreatic fistula and conduct timely treatment thereafterRecent research standardized the definition of pancreatic fistula and stressed the correlation betweenAccording to the literature, identification of the risk factors for pancreatic fistula contributed toAppropriate management of the pancreatic stump and perioperative treatment are of great significance

Keywords： pancreatic fistula     pancreatic body and tail resection     distal pancreatectomy    

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The role of prophylactic transpapillary pancreatic stenting in distal pancreatectomy: a meta-analysis

Xiangsong Wu, Maolan Li, Wenguang Wu, Jiasheng Mu, Lin Zhang, Qichen Ding, Qian Ding, Hao Weng, Runfa Bao, Yijun Shu, Ping Dong, Jun Gu, Jianhua Lu, Yingbin Liu

Frontiers of Medicine 2013, Volume 7, Issue 4,   Pages 499-505 doi: 10.1007/s11684-013-0296-9

Abstract:

Pancreatic fistula (PF) is the most frequent complication after distal pancreatectomy (DP).Prophylactic transpapillary pancreatic stenting (PTPS) has been proposed recently for the prevention

Keywords： pancreatic fistula     distal pancreatectomy     pancreatic stent     meta-analysis    

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An analysis of clinico-pathologic features of intraductal papillary mucinous neoplasm of the pancreas

LOU Wenhui, JIN Dayong, WANG Dansong, XU Xuefeng, KUANG Tiantao, QIN Xinyu

Frontiers of Medicine 2007, Volume 1, Issue 2,   Pages 173-176 doi: 10.1007/s11684-007-0032-4

Abstract: The natural history and clinical manifestation of resected intraductal papillary mucinous neoplasm (IPMN) of the pancreas were elucidated, and based on this, a retrospective pancreatic database was reviewedThe average diameter of the pancreatic duct was also wider in the invasive group (8.7 mm 4.3 mm).predictors of malignant IPMNs included weight loss, jaundice, a high level of serum CA19-9, a large pancreatic

Keywords： diameter     Pathologic rereview     invasive     unresectable     intraductal papillary    

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Influence of the adjuvant therapy on the survival of patients with stage II pancreatic carcinoma

Xi-Yan WANG, Hai-Jun LI, Dong YAN, Hao WEN, Shu-Yong PENG,

Frontiers of Medicine 2010, Volume 4, Issue 4,   Pages 430-435 doi: 10.1007/s11684-010-0700-7

Abstract: This study aimed to investigate the effect of adjuvant therapy on the treatment of stage II pancreaticThe clinical data of 139 cases of stage II pancreatic carcinoma were analyzed retrospectively.be suggested according to the general condition of the patients after radical resection for stage II pancreatic

Keywords： pancreatic neoplasms     neoadjuvant therapy     survival    

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Analysis of 100 consecutive cases of resectable pancreatic neuroendocrine neoplasms: clinicopathological

Yugang Cheng,Hanxiang Zhan,Lei Wang,Jianwei Xu,Guangyong Zhang,Zongli Zhang,Sanyuan Hu

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 444-450 doi: 10.1007/s11684-016-0471-x

Abstract:

The incidence rate of pancreatic neuroendocrine neoplasms (pNENs) has increased rapidly in recent

Keywords： pancreatic neuroendocrine neoplasms     clinicopathological characteristic     Ki-67     liver metastasis     outcomes    

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Laparoscopic hepato-biliary-pancreatic surgery: present practices and prospects

Yongjun Chen, Renyi Qin, Xiaoping Chen

Frontiers of Medicine 2011, Volume 5, Issue 3,   Pages 235-238 doi: 10.1007/s11684-011-0156-4

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Improving the prognosis of pancreatic cancer: insights from epidemiology, genomic alterations, and therapeutic

Frontiers of Medicine doi: 10.1007/s11684-023-1050-6

Abstract: Pancreatic cancer, notorious for its late diagnosis and aggressive progression, poses a substantial challengeThis review endeavors to furnish a holistic insight into pancreatic cancer, encompassing its epidemiologyexposures, and explore recent research advancements in precursor lesions and molecular subtypes of pancreaticAdditionally, we highlight the development and application of multi-omics approaches in pancreatic cancerresearch and discuss the latest combinations of pancreatic cancer biomarkers and their efficacy.

Keywords： pancreatic cancer     cancer screening     single cell     molecular alterations     precancerous lesion     therapy    

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Immunotherapeutic effects on murine pancreatic carcinoma by β-elemene combined with dendritic cells modified

TAN Guang, WANG Zhongyu, CHE Luanqing, YIN Shuo

Frontiers of Medicine 2007, Volume 1, Issue 1,   Pages 41-45 doi: 10.1007/s11684-007-0008-4

Abstract: The dendritic cell vaccine is a treatment vaccine with potent clinical applications. Functional cytokines can enhance dendritic cell anti-tumor immune responses. This experiment was conducted to study the effects of bone marrow-deriv

Keywords： Functional     experiment     anti-tumor     dendritic     clinical    

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Total pancreatic necrosis after organophosphate intoxication

Rui Hou, Hongmin Zhang, Huan Chen, Yuankai Zhou, Yun Long, Dawei Liu

Frontiers of Medicine 2019, Volume 13, Issue 2,   Pages 285-288 doi: 10.1007/s11684-018-0626-z

Abstract: occasionally in clinics, but very few of them develop into severe pancreas necrosis and irreversible pancreaticShe received percutaneous catheterization and drainage of pancreatic zone to expel hazardous necroticpancreatin capsules before meals and hypodermic insulin at meals and bedtime to compensate the impaired pancreatic

Keywords： organophosphate intoxication     severe acute pancreatitis     pancreas necrosis     percutaneous catheterization     sandostatin     insulin    

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Acetylated HOXB9 at lysine 27 is of differential diagnostic value in patients with pancreatic ductal

Xiaoran Sun, Jiagui Song, Jing Zhang, Jun Zhan, Weigang Fang, Hongquan Zhang

Frontiers of Medicine 2020, Volume 14, Issue 1,   Pages 91-100 doi: 10.1007/s11684-019-0696-6

Abstract: Pancreatic ductal adenocarcinoma (PDAC) is the ninth most common human malignancy and the sixth leadingTissue microarrays consisting of 162 pancreatic tumor tissue samples from patients with PDAC and paired

Keywords： HOXB9     AcK27-HOXB9     PDAC    

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Effect of end-to-end invagination pancreaticojejunostomy with circle discontinuous U suture in pancreatic

ZHANG Xuewen, XUAN Wei, JIANG Tao, JI Degang, YANG Yongsheng, ZHANG Dan, XIE Yingjun, MENG Zihui, ZHAO Jisheng

Frontiers of Medicine 2007, Volume 1, Issue 1,   Pages 46-48 doi: 10.1007/s11684-007-0009-3

Abstract: The aim of this paper is to summarize the methods of pancreaticojejunostomy in the pancreatic operationThe incidences of pancreatic fistula with different types of pancreaticojejunostomy were compared.The overall incidence rate of pancreatic fistula was 26.5% (22/83).No pancreatic fistula occurred in end-to-end invagination pancreaticojejunostomy with circle discontinuousinvagination pancreaticojejunostomy with circle discontinuous U suture has a definite effect on avoiding pancreatic
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A ruptured recurrent small bowel gastrointestinal stromal tumour causing hemoperitoneum

Eric C.H. Lai,Kam Man Chung,Stephanie H.Y. Lau,Wan Yee Lau

Frontiers of Medicine 2015, Volume 9, Issue 1,   Pages 108-111 doi: 10.1007/s11684-014-0344-0

Abstract:

Hemoperitoneum is a rare and potentially life-threatening complication of GIST. We reported a 54-year-old man who developed disseminated intra-abdominal recurrence from a previously resected gastrointestinal stromal tumour (GIST) of the small bowel, and the patient presented with hemoperitoneum. Emergent debulking surgery was performed. A high dose imatinib was prescribed. Despite the presence of residual disease, the patient was well clinically 8 months after the operation. Even though, there is no evidence to support the routine use of debulking surgery in the management of GIST. In our patient, disease progression after second line targeted therapy and the absence of alternative treatment options for spontaneous rupture and hemoperitoneum prompted us to treat the patient aggressively. Resection of the ruptured GIST was carried out for control of bleeding and to prevent recurrent bleeding in this patient with good surgical risks. During the treatment decision-making, the patient’s general condition, the risk of surgery and the extent of dissemination were taken into consideration. In this patient who presented with spontaneous rupture of a small intestinal GIST, the novel use of targeted therapy and aggressive surgical treatment produced reasonably good survival outcome.

Keywords： gastrointestinal stromal tumour     hemoperitoneum     small bowel GIST     small bowel neoplasm     imatinib    

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Paratesticular fibrous pseudotumor: a report of five cases and literature review

Zhicheng Zhang,Jun Yang,Mingchao Li,Wei Cai,Qingquan Liu,Tao Wang,Xiaolin Guo,Shaogang Wang,Jihong Liu,Zhangqun Ye

Frontiers of Medicine 2014, Volume 8, Issue 4,   Pages 484-488 doi: 10.1007/s11684-014-0325-3

Abstract: Fibrous pseudotumor is not a neoplasm but a reactive fibrous inflammatory hyperplasia.

Keywords： fibroma     inflammation     scrotum     testicular neoplasm    

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Title Author Date Type Operation

Laparoscopic surgery for pancreatic lesions: current status and future

Taiping Zhang, Xiao Du, Yupei Zhao

Journal Article

Robotic distal pancreatectomy versus conventional laparoscopic distal pancreatectomy: a comparative study for short-term outcomes

Eric C. H. Lai,Chung Ngai Tang

Journal Article

Prevention and treatment of pancreatic fistula after pancreatic body and tail resection: current status

Li Jiang, Deng Ning, Xiaoping Chen

Journal Article

The role of prophylactic transpapillary pancreatic stenting in distal pancreatectomy: a meta-analysis

Xiangsong Wu, Maolan Li, Wenguang Wu, Jiasheng Mu, Lin Zhang, Qichen Ding, Qian Ding, Hao Weng, Runfa Bao, Yijun Shu, Ping Dong, Jun Gu, Jianhua Lu, Yingbin Liu

Journal Article

An analysis of clinico-pathologic features of intraductal papillary mucinous neoplasm of the pancreas

LOU Wenhui, JIN Dayong, WANG Dansong, XU Xuefeng, KUANG Tiantao, QIN Xinyu

Journal Article

Influence of the adjuvant therapy on the survival of patients with stage II pancreatic carcinoma

Xi-Yan WANG, Hai-Jun LI, Dong YAN, Hao WEN, Shu-Yong PENG,

Journal Article

Analysis of 100 consecutive cases of resectable pancreatic neuroendocrine neoplasms: clinicopathological

Yugang Cheng,Hanxiang Zhan,Lei Wang,Jianwei Xu,Guangyong Zhang,Zongli Zhang,Sanyuan Hu

Journal Article

Laparoscopic hepato-biliary-pancreatic surgery: present practices and prospects

Yongjun Chen, Renyi Qin, Xiaoping Chen

Journal Article

Improving the prognosis of pancreatic cancer: insights from epidemiology, genomic alterations, and therapeutic

Journal Article

Immunotherapeutic effects on murine pancreatic carcinoma by β-elemene combined with dendritic cells modified

TAN Guang, WANG Zhongyu, CHE Luanqing, YIN Shuo

Journal Article

Total pancreatic necrosis after organophosphate intoxication

Rui Hou, Hongmin Zhang, Huan Chen, Yuankai Zhou, Yun Long, Dawei Liu

Journal Article

Acetylated HOXB9 at lysine 27 is of differential diagnostic value in patients with pancreatic ductal

Xiaoran Sun, Jiagui Song, Jing Zhang, Jun Zhan, Weigang Fang, Hongquan Zhang

Journal Article

Effect of end-to-end invagination pancreaticojejunostomy with circle discontinuous U suture in pancreatic

ZHANG Xuewen, XUAN Wei, JIANG Tao, JI Degang, YANG Yongsheng, ZHANG Dan, XIE Yingjun, MENG Zihui, ZHAO Jisheng

Journal Article

A ruptured recurrent small bowel gastrointestinal stromal tumour causing hemoperitoneum

Eric C.H. Lai,Kam Man Chung,Stephanie H.Y. Lau,Wan Yee Lau

Journal Article

Paratesticular fibrous pseudotumor: a report of five cases and literature review

Zhicheng Zhang,Jun Yang,Mingchao Li,Wei Cai,Qingquan Liu,Tao Wang,Xiaolin Guo,Shaogang Wang,Jihong Liu,Zhangqun Ye

Journal Article